"Our findings, for the first time, suggest that males and females respond to high-fat diets differently," said Deborah Clegg of the Cedar-Sinai Diabetes And Obesity Research Institute in Los Angeles. "The data would suggest that is probably 'ok' for females to occasionally have a high-fat meal, where it is not recommended for males.
"The way we treat patients and provide dietary and nutritional advice should be altered. We might be less concerned about an occasional hamburger for women, but for men, we might more strongly encourage avoidance, especially if they have pre-existing diseases such as heart disease or type 2 diabetes."
Earlier data from Clegg's team and others had suggested that inflammation in the brain is tied to overeating, blood sugar imbalances, and increased inflammation in other parts of the body, including fat tissue. Those effects can be triggered, in males in particular, by short-term exposure to a high-fat diet.
The researchers say they were initially shocked to discover that male and female brains differ in their fatty acid composition. When they manipulated male mouse brains to have the fatty acid profile of females, they found that those animals were protected from the ill effects of a diet high in fat.
When males with average male brains entered an inflammatory state after eating diets high in fat, they also suffered from reduced cardiac function in a way that female animals in the study did not. Those sex differences in the brain's response to fat are related to differences between females and males in estrogen and estrogen receptor status.
If I had to advise Apple, it wouldn’t be to use a fancy SIM card that can be remotely changed, but instead to use an Apple-proprietary SIM card that contains no changeable data and is fully controlled by Apple. Then, the consumer could buy access to mobile networks throughout the world either through post-paid or pre-paid options offered by Apple. Apple would manage the subscriptions and authenticate the users on the correct networks. The user could switch mobile networks but have all of it managed by Apple.
Note that this is on the data-only iPad - voice regulations are complex. But we're getting away from the notion of voice as a service. This could be an interesting development,
The company behind Whisper, the social media app that promises users anonymity and claims to be “the safest place on the internet”, is tracking the location of its users, including some who have specifically asked not to be followed.
The practice of monitoring the whereabouts of Whisper users – including those who have expressly opted out of geolocation services – will alarm users, who are encouraged to disclose intimate details about their private and professional lives.
Whisper is also sharing information with the US Department of Defense gleaned from smartphones it knows are used from military bases, and developing a version of its app to conform with Chinese censorship laws.
The US version of the app, which enables users to publish short messages superimposed over photographs or other images, has attracted millions of users, and is proving especially popular among military personnel who are using the service to make confessions they would be unlikely to publish on Facebook or Twitter.
There are several barriers that prevent bike riding from becoming more popular in the US. Perhaps the largest is real and perceived safety. Minneapolis used some relatively small amounts of funding to a create a separate paths for bikes using an old path system dating back to the Depression. It isn't perfect by any means, but is a very different approach.